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ET ET 387 0 obj<> stream ET EMC Here is part 1 of the transcript of the excellent lecture given by Dr Robert Lustig. 72.000000 275.000000 Td /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw (Association. 0000108145 00000 n ET endobj 72.000000 397.000000 Td 72.000000 408.000000 Td BT ET In a special event hosted by the County Office of Education on March 24, 2011, Dr. Robert Lustig, Professor of Clinical Pediatrics, in the Division of Endocr. 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BT (adopted our diet all suffer now from the same problem, and were going to get even ) Tj 0.000000 0.000000 0.000000 rg endobj endobj stream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw A little extra sugar may seem harmless, but ingested often, it can contribute to a variety of health issues, like obesity, diabetes, and heart disease. endobj BT BT EMC 0000009816 00000 n No, they are not in the fat. 5 grams ) Tj endobj 851 0 obj<> ET 0000196758 00000 n 300 0 obj<> (policy in this world to draw on in terms of how to limit consumption, because ethanol is ) Tj 72.000000 118.000000 Td endstream BT The answer is any amount. 721 0 obj<> ET 0000052174 00000 n /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 0000085090 00000 n 105 0 obj<> /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 72.000000 475.000000 Td 0000051034 00000 n ET (that you might find coming out of you instead going into you. 96 0 obj<> 72.000000 286.000000 Td stream 41 0 obj<> EMC endobj (the top. 0000053108 00000 n 0000013307 00000 n So that will be worth 26 pounds of fat per year if you did that ) Tj endstream ET endobj EMC /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 156 0 obj<> 72.000000 383.000000 Td (fructose is a poison. ET 388 0 obj<> ET BT stream (that were independent. (- written by a British physiologist, nutritionist, endocrinologist by the name of John ) Tj 0000214981 00000 n endstream ET How about the FDA? ET endobj EMC BT They make the stuff that lets you live called ATP - ATP adenosine ) Tj Tj ET 72.000000 374.000000 Td ET endstream endstream (All right you get the picture. endstream 72.000000 543.000000 Td So why is there so much sugar in Coke? 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EMC EMC EMC stream 72.000000 709.000000 Td EMC stream Tj EMC /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT (in normal negative yin yang energy balance. 459 0 obj<> endstream This acetyl-CoA and this ethanol and this ) Tj ET endstream BT (Nonetheless here's Center for the Science in the Public Interest \(CSPI\) and the Corn ) Tj Tj ET endobj endstream So any hypothesis that you want to proffer that explains the obesity epidemic,) Tj endobj BT BT 0000126903 00000 n (to a low-fat diet. ET I am done and I can burn energy ) Tj 72.000000 151.000000 Td 191 0 obj<> Partial correlation analyses show ) Tj endstream Why are the Chinese? stream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 72.000000 285.000000 Td (corn syrup and sucrose. BT EMC ET endobj 715 0 obj<> (about not giving your kid a Budweiser but you don't think twice about giving your kid a ) Tj EMC /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw ET After all you see anybody on the street, hes a glutton and slough. 162 0 obj<> endstream You can actually see the color change too. (phosphate? BT BT 72.000000 207.000000 Td EMC EMC 209 0 obj<> endstream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 72.000000 128.000000 Td BT Tj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw stream EMC endstream stream stream BT ET BT /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 121 0 obj<> 477 0 obj<> 598 0 obj<> 290 0 obj<> Right, fat kids. ) BT 615 0 obj<> endobj So any hypothesis that you want to proffer that explains the obesity epidemic, youve got to explain this one too. stream 0000117509 00000 n stream Why are the Australians? Everybody's heard of ) Tj (going to tyrosine phosphorylated and this would be tyrosine IRS-1 which is now active. ) 0000184819 00000 n /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw stream stream 0000085995 00000 n /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw (the next hour, because I think there's another way to state the law, which is much more ) Tj 0000218502 00000 n EMC stream If you ask the scientist for the National Soft Drink ) Tj ET 72.000000 96.000000 Td (obese six month olds. endobj 0000060525 00000 n ET (also causes us satiety issues. endstream [6] And this is only what the government recommends, which at 8% sugar per meal is extraordinarily high! Tj EMC BT ET /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw So high fructose corn syrup is evil, but it's not evil because it's metabolically ) Tj EMC Well, the only way to do that was to make food cheap. BT endstream stream endstream 330 0 obj<> 189 0 obj<> /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endstream 0000162139 00000 n endobj High fructose corn syrup. endstream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw ET Well JNK-1, what it does is its serine phosphorylates ) Tj (reactive oxygen species can start this enzyme and activate it. 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(steatosis through that DNL pathway, those three enzymes, the new fat making pathway; ) Tj BT ET /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw Now why did ) Tj So when you consume fructose you're not consuming the carbohydrate; ) Tj ET endstream endstream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT EMC /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw (years ago used to consume 100 grams to 300 grams of fiber per day. endstream BT 487 0 obj<> BT 0000001569 00000 n BT 429 0 obj<> endstream ("My hairdresser says that sugar is healthier than high fructose corn syrup." (and actually causes what we call developmental programming changing the kids adiposity ) Tj (whatever you want to call it, 44 ounces worth 57 pounds of fat per year and if that ) Tj EMC 0000081806 00000 n 72.000000 305.000000 Td (No question about it. 0000033113 00000 n endobj stream stream 82 0 obj<> 906 0 obj<> BT endstream BT ET endstream EMC /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT I ) Tj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endstream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 72.000000 631.000000 Td 72.000000 152.000000 Td 622 0 obj<> (all fructose corn syrup. endobj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw So lets consume 120 calories in sucrose, a glass of orange juice. 0000125003 00000 n /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 72.000000 463.000000 Td So ) Tj ET 400 0 obj<> 656 0 obj<> 0000112296 00000 n ET endstream endstream 694 0 obj<> As far as I'm ) Tj It's how they are not the same.) endstream endstream 72.000000 542.000000 Td endobj It's also ) Tj 0000194132 00000 n stream ET 69 0 obj<> endstream endstream stream endobj EMC stream endobj 72.000000 362.000000 Td We as human beings, walking the earth 50,000 ) Tj EMC stream stream 0000129005 00000 n endobj EMC ( I am busy metabolizing my breakfast; I don't need lunch. endstream stream 752 0 obj<> 72.000000 284.000000 Td endobj (to show you that. 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ET ET 548 0 obj<> stream Thats worth 15.5 pounds of fat per year. ) (attempt by Pepsi to capture market share on the juice market. 72.000000 720.000000 Td 72.000000 720.000000 Td 72.000000 509.000000 Td ET But nonetheless there are 275 calories we have to ) Tj EMC ET 0000072952 00000 n /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw stream 0000153849 00000 n endobj ET endstream endstream BT (way and high-fat diet gets in the way. ET 0000190172 00000 n ET ET /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw (The Bitter Truth About Sugar by Robert Lustig Slides [PDF file]) Tj ET EMC endstream endobj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 0.000000 0.000000 0.000000 rg Every processed food. ET ( We had so far exceeded and surpassed this - its not even funny - from 2003. endobj Sugar: The Bitter Truth 7/27/2009; 89 minutes Robert H. Lustig, MD, UCSF Professor of Pediatrics in the Division of Endocrinology, explores the damage caused by sugary foods. Its like a glass of milk plus a half a glass of orange juice, ) Tj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endobj (something called Acetyl-CoA, which then gets packaged with this protein here and you end ) Tj ET This we are suffering from it today. BT ET 0000087669 00000 n 72.000000 308.000000 Td BT 72.000000 720.000000 Td (Why is exercise important in obesity) Tj (we've actually gotten rid of most trans fats, not completely, but most. 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EMC BT ( ) Tj endstream 0000201781 00000 n stream 72.000000 264.000000 Td 54 0 obj<> EMC 72.000000 274.000000 Td Tj We call that a poison. ) 72.000000 664.000000 Td BT 72.000000 309.000000 Td endobj 297 0 obj<> ET BT (because they take the fiber out, because that way they can freeze it, ship it around the ) Tj Tj endstream EMC 0000210471 00000 n BT We cant check the work. ET 197 0 obj<> endobj 72.000000 507.000000 Td BT BT 0000132739 00000 n BT endstream 469 0 obj<> stream EMC endobj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 0000166192 00000 n stream (the price of sugar when this thing hit the market? EMC ET stream endstream (based 30 years of nutrition education and information and policy in this country on this ) Tj endobj 72.000000 531.000000 Td So ) Tj BT 72.000000 454.000000 Td stream endstream 585 0 obj<> EMC 0000134329 00000 n BT /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT They are not ) Tj endstream 719 0 obj<> EMC /FNT_Courier_Bold 9.090909 Tf 95.000000 Tz 0.000000 Tw endobj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endstream 0000209748 00000 n endobj 0000070819 00000 n stream The fat is going down. EMC stream said well if A leads to B ) Tj BT 0000188252 00000 n BT EMC /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw ET BT Tj EMC endobj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endstream 72.000000 531.000000 Td So here is what JNK-1 does. BT Tj 72.000000 298.000000 Td 72.000000 687.000000 Td endobj stream 217 0 obj<> stream BT endobj endobj 0000130683 00000 n endstream stream EMC Remember the first pass GI metabolism takes ) Tj BT (of the earth can use glucose because glucose is the energy of life. Tj 0000152443 00000 n BT 911 0 obj<> endstream stream ET endobj stream EMC stream endstream endobj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endobj endstream EMC stream Sure enough we are all eating more now ) Tj Tj endobj endobj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 72.000000 274.000000 Td (Hepatic fructose metabolism leads to all the manifestations of the metabolic syndrome ) Tj 499 0 obj<> ET Sugared beverage consumption. endobj 611 0 obj<> endobj stream stream BT stream 125 0 obj<> 72.000000 352.000000 Td EMC 0000185567 00000 n /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 70 0 obj<> 0000093493 00000 n endstream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT EMC stream 72.000000 271.000000 Td stream 375 0 obj<> /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 0000148007 00000 n endobj 0000131169 00000 n endstream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw stream endobj endobj ET ET endstream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 72.000000 653.000000 Td endstream Tj So 24 calories right off the top. (leptin resistance promoting continuous consumption, basically starving your brain, making ) Tj stream endobj 72.000000 316.000000 Td 31 0 obj<> 72.000000 141.000000 Td 0000211660 00000 n /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 0000217543 00000 n Now sometimes that's bad. endobj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 326 0 obj<> EMC (I want to show you the difference between glucose and fructose in a way that will be ) Tj endobj Now lets talk about calorie intake, because thats what today is about. EMC /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw (Obesity epidemic) Tj endobj stream endobj endobj endobj Lets talk about my favorite ) Tj ET 72.000000 597.000000 Td Were all eating more. /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT Tj endobj 195 0 obj<> endobj ET Tj EMC 72.000000 497.000000 Td BT 0000057214 00000 n 0 915 endstream endstream stream endstream 72.000000 532.000000 Td (About Sugar" slides below while reading this transcript) Tj stream 799 0 obj<> This is not dangerous. endstream EMC 72.000000 252.000000 Td 0000215702 00000 n 220 0 obj<> stream BT 829 0 obj<> endstream stream EMC BT endstream BT /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw ET stream EMC stream ET ET endstream (So now comes the fun part - the racial innuendos and all the political stuff - the ) Tj 72.000000 575.000000 Td 0000158603 00000 n endstream stream stream Not "may", "does".) 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